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Differential changes in Cu, Zn and Mn superoxide dismutase activity in developing rat brain and liver
G Mariucci1, M V Ambrosini, L Colarieti
1Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Italy.
Experientia
|July 15, 1990
Abstract:
The aim of our study was to assess the pattern of copper and zinc-containing superoxide dismutase (Cu, ZnSOD) and manganese-containing superoxide dismutase (MnSOD) activity from embryonic life to senescence in rat brain and liver. The two isoenzymes showed different profiles in the two organs examined. In particular, the cerebral MnSOD activity profile suggests a primary role during differentiation of this enzymatic form.