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Related Concept Videos

Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic sinusitis...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...

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Related Experiment Video

Updated: May 10, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

Care pathways for managing invasive mould diseases.

J Peter Donnelly1

  • 1Department of Haematology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands. p.donnelly@hemat.umcn.nl

International Journal of Antimicrobial Agents
|June 5, 2013
PubMed
Summary

Recent advances in managing invasive fungal diseases allow for personalized treatment strategies beyond empirical therapy. This shift improves patient care for those at risk, meeting specific prerequisites for tailored approaches.

Related Experiment Videos

Last Updated: May 10, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

Area of Science:

  • Mycology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Invasive fungal diseases (IFDs) pose significant challenges in clinical settings.
  • Historically, empirical therapy has been the mainstay for managing IFDs in at-risk patients.
  • Recent progress has created opportunities for more refined treatment protocols.

Purpose of the Study:

  • To highlight recent advancements in the diagnosis and treatment of IFDs.
  • To discuss the evolving approach towards individualized patient care for IFDs.
  • To outline the prerequisites for implementing personalized IFD management.

Main Methods:

  • Review of recent literature on IFD management.
  • Analysis of updated definitions and diagnostic criteria for IFDs.
  • Evaluation of new therapeutic agents and strategies for IFDs.

Main Results:

  • Significant improvements in IFD definitions and diagnostic accuracy.
  • Development of novel antifungal drugs and treatment regimens.
  • Growing recognition of the feasibility of individualized IFD therapy.

Conclusions:

  • The management of IFDs has evolved favorably over the past decade.
  • Individualized treatment approaches are now possible for at-risk patients with IFDs.
  • Meeting specific prerequisites is essential for successful personalized IFD management.