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[Ocular involvement in congenital Chagas disease]

Griselda Berberian1, María Teresa Rosanova, Carina Kaldzielski

  • 1Control Epidemiológico e Infectología, Hospital de Pediatría Prof. Dr. J. P. Garrahan, Buenos Aires, Argentina. griselberberian@yahoo.com.ar

Archivos Argentinos De Pediatria
|June 5, 2013
PubMed

Insights

Congenital Chagas disease can cause severe eye problems like bilateral vitreitis in newborns. Early diagnosis and antiparasitic treatment lead to good outcomes for affected infants.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Pediatrics

Background:

  • Congenital Chagas disease is a rare cause of ophthalmic issues in infants.
  • Ocular involvement in congenital Chagas disease is infrequently reported.
  • Premature infants with congenital infections require specialized ophthalmic evaluation.

Observation:

  • Three infants under two months old presented with ocular symptoms.
  • All patients were referred for ophthalmic evaluation due to prematurity.
  • The primary ophthalmic finding was severe bilateral vitreitis (posterior uveitis).

Findings:

  • The vitreitis was directly attributed to congenital Chagas disease.
  • Affected infants received antiparasitic therapy.
  • All patients demonstrated a positive clinical response to treatment.

Implications:

  • Chagas disease should be considered in the differential diagnosis of pediatric ocular pathology in endemic regions.
  • Fundoscopic examination is crucial for infants diagnosed with Chagas disease, particularly symptomatic and premature newborns.
  • Prompt diagnosis and treatment of congenital Chagas disease can prevent severe visual impairment.

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