Trends in bronchiolitis hospitalizations in the United States, 2000-2009

Kohei Hasegawa1, Yusuke Tsugawa, David F M Brown

  • 1Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA. khasegawa1@partners.org

Pediatrics
|June 5, 2013
PubMed

Insights

Bronchiolitis hospitalizations in US children decreased 17% between 2000-2009. However, mechanical ventilation use and hospital charges for bronchiolitis significantly increased during this period.

Area of Science:

  • Pediatric Pulmonology
  • Health Services Research
  • Epidemiology

Background:

  • Bronchiolitis is a common viral respiratory infection in infants and young children.
  • Hospitalization rates and associated costs for bronchiolitis have been a growing concern.
  • Understanding temporal trends is crucial for resource allocation and public health strategies.

Purpose of the Study:

  • To analyze trends in national bronchiolitis hospitalizations among US children under 2 years old.
  • To evaluate changes in the utilization of mechanical ventilation for bronchiolitis cases.
  • To assess the temporal trends in hospital charges associated with bronchiolitis from 2000 to 2009.

Main Methods:

  • A serial, cross-sectional analysis using the Kids Inpatient Database (KID).
  • Identification of bronchiolitis cases using ICD-9-CM code 466.1 for children <2 years.
  • Evaluation of temporal trends in hospitalization incidence, mechanical ventilation use, and hospital charges, accounting for sampling weights.

Main Results:

  • Bronchiolitis hospitalization incidence decreased by 17% (17.9 to 14.9 per 1000 person-years) between 2000 and 2009.
  • There was a significant increase in the proportion of hospitalized children with high-risk conditions (34%) and mechanical ventilation use (21%).
  • Nationwide hospital charges for bronchiolitis rose by 30% ($1.34 billion to $1.73 billion), with a 34% increase in mean charges per case.

Conclusions:

  • A significant decline in bronchiolitis hospitalizations was observed in US children from 2000 to 2009.
  • Despite decreased hospitalizations, mechanical ventilation use and hospital charges for bronchiolitis substantially increased during the same period.
  • These findings highlight evolving treatment patterns and escalating healthcare costs for pediatric bronchiolitis.
Abstract

Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...