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Trends in bronchiolitis hospitalizations in the United States, 2000-2009
Kohei Hasegawa1, Yusuke Tsugawa, David F M Brown
1Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA. khasegawa1@partners.org
Insights
Bronchiolitis hospitalizations in US children decreased 17% between 2000-2009. However, mechanical ventilation use and hospital charges for bronchiolitis significantly increased during this period.
Area of Science:
- Pediatric Pulmonology
- Health Services Research
- Epidemiology
Background:
- Bronchiolitis is a common viral respiratory infection in infants and young children.
- Hospitalization rates and associated costs for bronchiolitis have been a growing concern.
- Understanding temporal trends is crucial for resource allocation and public health strategies.
Purpose of the Study:
- To analyze trends in national bronchiolitis hospitalizations among US children under 2 years old.
- To evaluate changes in the utilization of mechanical ventilation for bronchiolitis cases.
- To assess the temporal trends in hospital charges associated with bronchiolitis from 2000 to 2009.
Main Methods:
- A serial, cross-sectional analysis using the Kids Inpatient Database (KID).
- Identification of bronchiolitis cases using ICD-9-CM code 466.1 for children <2 years.
- Evaluation of temporal trends in hospitalization incidence, mechanical ventilation use, and hospital charges, accounting for sampling weights.
Main Results:
- Bronchiolitis hospitalization incidence decreased by 17% (17.9 to 14.9 per 1000 person-years) between 2000 and 2009.
- There was a significant increase in the proportion of hospitalized children with high-risk conditions (34%) and mechanical ventilation use (21%).
- Nationwide hospital charges for bronchiolitis rose by 30% ($1.34 billion to $1.73 billion), with a 34% increase in mean charges per case.
Conclusions:
- A significant decline in bronchiolitis hospitalizations was observed in US children from 2000 to 2009.
- Despite decreased hospitalizations, mechanical ventilation use and hospital charges for bronchiolitis substantially increased during the same period.
- These findings highlight evolving treatment patterns and escalating healthcare costs for pediatric bronchiolitis.
Objective:
To examine temporal trend in the national incidence of bronchiolitis hospitalizations, use of mechanical ventilation, and hospital charges between 2000 and 2009.
Methods:
We performed a serial, cross-sectional analysis of a nationally representative sample of children hospitalized with bronchiolitis. The Kids Inpatient Database was used to identify children <2 years of age with bronchiolitis by International Classification of Diseases, Ninth Revision, Clinical Modification code 466.1. Primary outcome measures were incidence of bronchiolitis hospitalizations, mechanical ventilation (noninvasive or invasive) use, and hospital charges. Temporal trends were evaluated accounting for sampling weights.
Results:
The 4 separated years (2000, 2003, 2006, and 2009) of national discharge data included 544 828 weighted discharges with bronchiolitis. Between 2000 and 2009, the incidence of bronchiolitis hospitalization decreased from 17.9 to 14.9 per 1000 person-years among all US children aged <2 years (17% decrease; P(trend) < .001). By contrast, there was an increase in children with high-risk medical conditions (5.9%-7.9%; 34% increase; P(trend) < .001) and use of mechanical ventilation (1.9%-2.3%; 21% increase; P(trend) = .008). Nationwide hospital charges increased from $1.34 billion to $1.73 billion (30% increase; P(trend) < .001); this increase was driven by a rise in the geometric mean of hospital charges per case from $6380 to $8530 (34% increase; P(trend) < .001).
Conclusions:
Between 2000 and 2009, we found a significant decline in bronchiolitis hospitalizations among US children. By contrast, use of mechanical ventilation and hospital charges for bronchiolitis significantly increased over this same period.
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