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Differential Roles of PML Isoforms.

Sébastien Nisole1, Mohamed Ali Maroui, Xavier H Mascle

  • 1INSERM UMR-S 747 Paris, France ; Université Paris Descartes Paris, France.

Frontiers in Oncology
|June 5, 2013
PubMed
Summary

The promyelocytic leukemia (PML) protein is crucial in acute promyelocytic leukemia (APL). This review clarifies PML isoform structures, functions, and their degradation pathways, aiding APL treatment research.

Keywords:
As2O3CK2PML isoformsPML nomenclatureRNF4SIMSUMOTRIMvirus

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