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Updated: May 10, 2026

Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System
Published on: September 20, 2019
Analytical results on the Beauchemin model of lymphocyte migration
Johannes Textor1, Mathieu Sinn, Rob J de Boer
1Theoretical Biology & Bioinformatics, Utrecht University, Utrecht, The Netherlands. johannes.textor@gmx.de
Abstract:
The Beauchemin model is a simple particle-based description of stochastic lymphocyte migration in tissue, which has been successfully applied to studying immunological questions. In addition to being easy to implement, the model is also to a large extent mathematically tractable. This article provides a comprehensive overview of both existing and new analytical results on the Beauchemin model within a common mathematical framework. Specifically, we derive the motility coefficient, the mean square displacement, and the confinement ratio, and discuss four different methods for simulating biased migration of pre-defined speed. The results provide new insight into published studies and a reference point for future research based on this simple and popular lymphocyte migration model.

