Related Experiment Video
Updated: May 10, 2026
04:55
Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation After Prolonged Circulatory Arrest
Published on: May 26, 2023
Pediatric extracorporeal life support in specialized situations
V Ben Sivarajan1, Mel C Almodovar, Mark D Rodefeld
1Department of Critical Care Medicine, The Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, ON, Canada. ben.sivarajan@sickkids.ca
Summary
Extracorporeal life support (ECLS) evidence for specialized pediatric conditions is mostly class II-III. Class I indications include myocarditis and cardiac catheterization interventions.
Area of Science:
- Pediatric Cardiology
- Critical Care Medicine
- Cardiovascular Surgery
Background:
- Extracorporeal life support (ECLS) is a vital intervention for critically ill children.
- Specialized applications of ECLS require clear evidence-based guidelines.
Purpose of the Study:
- To systematically review the literature on ECLS use in specialized pediatric conditions.
- To inform the Pediatric Cardiac Intensive Care Society/Extracorporeal Life Support Organization Joint Statement.
Main Methods:
- Comprehensive literature search of MEDLINE and PubMed.
- Inclusion of case reports and studies focusing on non-respiratory ECLS indications.
- Review of outcomes such as survival to hospital discharge.
Main Results:
- Evidence for most specialized ECLS uses is classified as class II-III.
- Studies were evaluated using the American College of Cardiology Foundation/American Heart Association format.
Conclusions:
- Class I indications for pediatric ECLS include myocarditis.
- ECLS is also a class I option during acute cardiac catheterization interventions.
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