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Updated: May 10, 2026

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
Characteristics of perinatal women seeking treatment for marijuana abuse in a community-based clinic
Golfo Tzilos1, Lynn Hess, Jennifer Chien-Wen Kao
1Center for Alcohol and Addiction Studies, Alpert Medical School of Brown University, Box G-S121-4, Providence, RI 02912, USA. Golfo_Tzilos@brown.edu
Unlabelled:
In the US, marijuana continues to be the most frequently used illicit drug among women of childbearing age, including pregnant and postpartum women. Given the critical window for treatment during the perinatal period, more information is needed about the characteristics of women who abuse marijuana and about their unique needs with the goal of improving clinical services and outcomes for both women and their infants.
Objectives:
To (1) identify a profile of perinatal women seeking treatment for primarily marijuana abuse and (2) report birth outcomes in a subset of pregnant women with marijuana abuse.
Methods:
This retrospective clinical chart review study examined 67 adult perinatal women patients (54 % ethnic minority) who attended an inner-city, hospital-affiliated outpatient program specializing in substance abuse treatment for women. Of all pregnant women, 26 % reported positive urine screens during the first trimester, 41 % during the second trimester, and 27 % during the third trimester. While the subset of pregnant women was small, exploratory results suggest that infants whose mothers continued to use marijuana during their pregnancies were born at a lower gestational age than mothers who abstained; t(29) = 2.04, p <0.05.
Conclusion:
Identifying potential barriers to treatment could help improve retention in community-based treatment programs during pregnancy and the postpartum period.
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