Related Experiment Video
Updated: May 10, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Nosocomial pulmonary tuberculosis contact investigation in a neonatal intensive care unit
Kate E Fisher1, Robert Guaran, Jacqueline Stack
1Department of Community Paediatrics, South Western Sydney Local Health District, Liverpool, New South Wales, Australia. kate.fisher@sswahs.nsw.gov.au
Insights
A medical officer with tuberculosis in an Australian neonatal unit did not transmit the infection. Contact tracing of 125 neonates, 165 relatives, and 122 staff found no evidence of nosocomial tuberculosis spread.
Area of Science:
- Infectious Diseases
- Public Health
- Neonatal Care
Background:
- A case of smear-positive pulmonary tuberculosis was diagnosed in a medical officer.
- The officer worked in a metropolitan Australian neonatal intensive care unit (NICU).
- This diagnosis necessitated a comprehensive contact investigation.
Purpose of the Study:
- To investigate potential tuberculosis transmission from an infectious medical officer to neonates, relatives, and healthcare workers.
- To assess the risk of nosocomial tuberculosis transmission in a high-risk NICU setting.
- To evaluate the effectiveness of contact tracing protocols following a tuberculosis diagnosis in a healthcare professional.
Main Methods:
- Contact tracing was performed for all individuals with potential exposure to the index case.
- The investigation included 125 neonates, 165 relatives, and 122 healthcare workers.
- Contact assessment involved evaluating the degree of exposure and clinical/radiological follow-up where indicated.
Main Results:
- No evidence of tuberculosis transmission was found from the index case.
- All investigated neonates, relatives, and healthcare workers tested negative for tuberculosis infection related to this index case.
- The contact investigation confirmed the absence of nosocomial spread within the NICU.
Conclusions:
- The study concluded that there was no nosocomial tuberculosis transmission from the diagnosed medical officer.
- This finding suggests effective infection control measures were in place or the exposure risk was minimal.
- Further vigilance in healthcare settings is crucial for preventing infectious disease transmission, especially in vulnerable neonatal populations.
Abstract:
The diagnosis of smear-positive pulmonary tuberculosis in a medical officer working in a metropolitan Australian neonatal intensive care unit led to a contact investigation involving 125 neonates, 165 relatives, and 122 healthcare workers with varying degrees of exposure. There was no evidence of nosocomial tuberculosis transmission from the index case.
Related Concept Videos
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...