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Updated: May 10, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
American tegumentary leishmaniasis: an uncommon clinical and histopathological presentation
Adrilena Lopes Adriano1, Paula Azevedo Borges Leal, Marcelle Parente Breckenfeld
1Dermatology Department, Dona Libânia Dermatology Center, Fortaleza, CE, Brazil. adrilena@hotmail.com
Abstract:
We report a case of an unusual presentation of American Tegumentary Leishmaniasis involving a male patient with a solitary lesion on the ear lobe, persisting with minimal increase for at least six months without ulceration or related symptoms. The histological sections showed epithelial atrophy and a large number of structures consistent with Leishmania sp. amastigotes within macrophages. Treatment commenced with meglumine antimoniate resulting in regression of the condition. This report is of importance given the unusual clinical manifestation and histopathological findings in this case and the fact that there was low correlation with the extended duration of the disease.
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