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[A case of Peutz-Jeghers syndrome with repeated small intestinal intussusception successfully treated by

Tomohiro Miyachi1, Naoki Tanaka, Katsuya Endo

  • 1Division of Biological Regulation and Oncology, Tohoku University Graduate School of Medicine, Japan. to_miyachi@surg1.med.tohoku.ac.jp

Nihon Shokakibyo Gakkai Zasshi = the Japanese Journal of Gastro-Enterology
|June 7, 2013
PubMed

Insights

Peutz-Jeghers syndrome (PJS) patients with intestinal intussusception can undergo simultaneous endoscopic polypectomy during surgery. This approach effectively removes polyps, preventing future complications without bowel resection.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Genetics

Background:

  • Peutz-Jeghers syndrome (PJS) is characterized by hamartomatous intestinal polyps.
  • These polyps can cause serious complications like intussusception and bleeding, often requiring repeated surgeries and bowel resections.
  • Preventing polyp recurrence is crucial in managing PJS patients.

Observation:

  • A young woman with PJS presented with small intestinal intussusception due to a polyp.
  • The surgical team opted for a combined approach: intussusception repair and endoscopic polypectomy.
  • This was performed without the need for small intestine resection.

Findings:

  • The procedure successfully addressed the intussusception.
  • Endoscopic polypectomy was performed during the operation.
  • All polyps exceeding 10mm, from the duodenum to the ascending colon, were resected.

Implications:

  • This case demonstrates the feasibility of simultaneous endoscopic polypectomy during intussusception repair in PJS patients.
  • Such an approach may reduce the need for extensive bowel resection and prevent future complications.
  • It highlights a potentially less invasive management strategy for PJS-related intussusception.

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