Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Keeping an eye on attentive listening: Task-evoked pupil size unveils fluctuations in auditory sustained attention.

Biological psychology·2025

Same author

Unconditional stability of a recurrent neural circuit implementing divisive normalization.

Advances in neural information processing systems·2025

Same author

Attention-induced perceptual traveling waves in binocular rivalry.

Journal of vision·2025

Same author

Contrastive Self-Supervised Learning As Neural Manifold Packing.

ArXiv·2025

Same author

Hierarchical Neural Circuit Theory of Normalization and Inter-areal Communication.

bioRxiv : the preprint server for biology·2025

Same author

Stabilization of recurrent neural networks through divisive normalization.

bioRxiv : the preprint server for biology·2025

Same journal

Vestibular function drives gaze stability in locomoting macaques.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

Same journal

Region- and layer-specific glutamatergic synapse development in the nascent cortical hierarchy.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

Same journal

Endogenous peptide derived from c-Cbl-associated protein counteracts its inhibitory effect on enteric neural crest cell colonization in Hirschsprung disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

Same journal

Drowsiness alters the neural dynamics but not the core computations of multisensory integration.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

Same journal

A Matter of Parameters: Tailored Transcranial Focused Ultrasound Enhances Cortico-Thalamo-Cortical Circuit Resonance.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

Same journal

Proactive visual and motor prioritization differentially scale with cue reliability.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 10, 2026

How to Create and Use Binocular Rivalry

How to Create and Use Binocular Rivalry

Published on: November 10, 2010

Continuous flash suppression modulates cortical activity in early visual cortex.

Shlomit Yuval-Greenberg¹, David J Heeger

¹Department of Psychology and Center for Neural Science, New York University, New York, New York 10003, USA. shlomitgr@tau.ac.il

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

|June 7, 2013

Summary

This summary is machine-generated.

Continuous flash suppression (CFS) makes stimuli invisible by flashing masks to one eye. This study reveals CFS modulates neural response gain in early visual cortex, akin to contrast reduction, resolving V1

More Related Videos

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

Related Experiment Videos

Last Updated: May 10, 2026

How to Create and Use Binocular Rivalry

How to Create and Use Binocular Rivalry

Published on: November 10, 2010

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

Area of Science:

Neuroscience
Visual Perception
Cognitive Science

Background:

Continuous flash suppression (CFS) renders stimuli invisible by presenting dichoptic stimuli.
CFS is a key method for studying awareness and visual perception.
The role of primary visual cortex (V1) in CFS remains controversial.

Purpose of the Study:

To resolve the controversy regarding V1's role in CFS.
To characterize the computational mechanisms underlying CFS.
To investigate how CFS affects early visual cortical activity.

Main Methods:

Functional magnetic resonance imaging (fMRI) was used to measure brain activity.
Human subjects viewed stimuli with varying target and mask contrasts.
Stimuli were presented to the same or different eyes (dichoptic presentation).

Main Results:

fMRI responses in early visual cortex were reduced when target and mask were presented to different eyes.
This suppression occurred for both invisible (low contrast) and visible (high contrast) targets.
The findings suggest CFS modulates neural response gain, similar to contrast reduction.

Conclusions:

CFS suppresses activity in early visual cortex, including V1.
The mechanism of CFS involves modulating neural response gain.
This gain modulation is comparable to reducing the physical contrast of the visual stimulus.