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Related Experiment Video

Updated: May 10, 2026

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

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[Nutrition and gastrointestinal intolerance].

C Madl¹, U Holzinger

¹4. Medizinische Abteilung mit Gastroenterologie, Hepatologie und Zentralendoskopie, Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030, Wien, Österreich. christian.madl@wienkav.at

Medizinische Klinik, Intensivmedizin Und Notfallmedizin

|June 7, 2013

Summary

Enteral nutrition is crucial for intensive care patients. Jejunal tubes effectively manage gastrointestinal dysfunction, improving nutrition delivery and reducing complications like pneumonia.

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Area of Science:

Gastroenterology and Critical Care Medicine

Context:

Gastrointestinal dysfunction affects up to 65% of intensive care unit (ICU) patients.
Symptoms include high gastric residual volume, vomiting, and abdominal distension, impairing enteral nutrition.
Pathophysiological alterations can lead to gastrointestinal intolerance, particularly gastroduodenal motility disorders and reflux.

Purpose:

To review the management of gastrointestinal intolerance in intensive care patients.
To highlight the efficacy of jejunal tubes for enteral nutrition delivery.
To discuss therapeutic options for improving gastrointestinal motility and intolerance.

Summary:

Jejunal tube placement enables adequate postpyloric enteral nutrition in over 90% of ICU patients with motility disorders.
This approach improves nutrition tolerance, reduces gastroesophageal reflux, and lowers the incidence of ventilation-associated pneumonia.
Advancements in jejunal tube placement techniques and therapeutic interventions offer solutions for gastrointestinal intolerance.

Impact:

Facilitates sufficient enteral nutrition in critically ill patients.
Reduces the incidence of serious complications such as ventilation-associated pneumonia.
Enhances patient outcomes through improved nutritional support and gastrointestinal function management.