Related Experiment Video
Updated: May 10, 2026
10:10
A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
Perforated tuberculosis lymphadenitis
Summary
A human immunodeficiency virus-positive man presented with symptoms of an opportunistic infection. Diagnosis revealed esophageal fistulae caused by Mycobacterium tuberculosis, a rare complication in immunocompromised individuals.
Area of Science:
- Infectious Diseases
- Pulmonology
- Gastroenterology
Background:
- Human immunodeficiency virus (HIV) infection can lead to opportunistic infections.
- Esophageal fistulae are rare but serious complications.
Observation:
- A 26-year-old HIV-positive male not on highly active antiretroviral treatment (HAART) presented with constitutional symptoms and chest pain.
- Imaging revealed esophageal to mediastinal fistulae.
- Biopsy and lavage identified Mycobacterium tuberculosis.
Findings:
- The patient was diagnosed with esophageal fistulae secondary to tuberculosis.
- This case highlights a rare presentation of disseminated tuberculosis in an immunocompromised individual.
Implications:
- Early diagnosis and treatment of opportunistic infections in HIV patients are crucial.
- Tuberculosis should be considered in the differential diagnosis of esophageal fistulae in immunocompromised patients.
- Further research into rare presentations of tuberculosis is warranted.
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