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Lexical fields of predictive and personalized medicine
Thierry Mathieu1, Laurent Bermont, Jean-Christophe Boyer
1Institut de Biologie Clinique Schaffner, Lens, LABCO, Paris, France.
Drug Metabolism and Drug Interactions
|June 7, 2013
Summary
The shift towards individualized therapies in medicine, driven by genomics and omics technologies, aims to prevent and cure diseases. This review clarifies personalized medicine, pharmacogenetics, genetics, and genomics for researchers and clinicians.
Area of Science:
- Genomic Medicine
- Translational Bioinformatics
Background:
- Advancements in human genome mapping and sequencing technologies have spurred the omics revolution.
- The early 21st century saw the development of powerful sequencing technologies.
Purpose of the Study:
- To contextualize personalized medicine, pharmacogenetics, genetics, and genomics.
- To emphasize the interactions between these fields.
- To discuss their significance for medical research and clinical practice.
Main Methods:
- Literature review and synthesis of current concepts.
- Analysis of the interplay between different 'omics' fields and medical applications.
Main Results:
- Personalized medicine represents a paradigm shift from population-based approaches.
- Pharmacogenetics, genetics, and genomics are foundational to individualized therapies.
- Understanding these concepts is crucial for advancing precision medicine.
Conclusions:
- Genomic technologies are enabling a transition to individualized healthcare.
- Pharmacogenetics and genomics are key to developing targeted therapies.
- This review provides a framework for understanding personalized medicine's components and implications.
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