Related Experiment Video
Updated: May 10, 2026
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Triplex-Inspector: an analysis tool for triplex-mediated targeting of genomic loci
Fabian A Buske1, Denis C Bauer, John S Mattick
1Division of Genomics and Computational Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.
Summary:
At the heart of many modern biotechnological and therapeutic applications lies the need to target specific genomic loci with pinpoint accuracy. Although landmark experiments demonstrate technological maturity in manufacturing and delivering genetic material, the genomic sequence analysis to find suitable targets lags behind. We provide a computational aid for the sophisticated design of sequence-specific ligands and selection of appropriate targets, taking gene location and genomic architecture into account.
Availability:
Source code and binaries are downloadable from www.bioinformatics.org.au/triplexator/inspector.
Contact:
t.bailey@uq.edu.au
Supplementary Information:
Supplementary data are available at Bioinformatics online.
