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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...

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Related Experiment Video

Updated: May 10, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Advanced glaucoma: management pearls.

Girum W Gessesse1, Karim F Damji

  • 1Department of Ophthalmology, College of Public Health and Medical Sciences, Jimma University, Ethiopia.

Middle East African Journal of Ophthalmology
|June 7, 2013
PubMed
Summary
This summary is machine-generated.

Late-stage glaucoma patients require a holistic approach. The biopsychosociospiritual (BPSS) model guides treatment to preserve vision and improve quality of life.

Keywords:
Advanced GlaucomaHolistic CareTrabeculectomy

Related Experiment Videos

Last Updated: May 10, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Area of Science:

  • Ophthalmology
  • Public Health

Background:

  • Many glaucoma patients, especially in developing regions, are diagnosed late with advanced disease.
  • These patients face imminent vision loss and socioeconomic/health challenges, causing patient anxiety and physician difficulty.

Purpose of the Study:

  • To propose a holistic, individualized biopsychosociospiritual (BPSS) model for managing advanced glaucoma.
  • To outline effective treatment strategies and supportive care for patients with advanced glaucoma.

Main Methods:

  • The BPSS model integrates ocular and systemic biology, psychological, socioeconomic, and spiritual factors.
  • Treatment decisions are made collaboratively with patients and care partners.

Main Results:

  • Aggressive intraocular pressure (IOP) lowering to the low teens or single digits is crucial for vision preservation.
  • Trabeculectomy with antimetabolites is often effective; medical/laser therapy may also be used.

Conclusions:

  • A comprehensive BPSS approach optimizes treatment for advanced glaucoma.
  • Vision rehabilitation and psychosocial support are vital for improving patient quality of life and hope.