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DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia

Kathrin E Bisling1, John N Brewin, Andrew P McGovern

  • 1Brighton and Sussex Medical School, University of Sussex , Brighton , UK.

Leukemia & Lymphoma
|June 8, 2013
PubMed
Abstract

No abstract available in PubMed .

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Translation01:31

Translation

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Translation01:31

Translation

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Mutations

Overview
Mutations01:35

Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
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The Ras Gene

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Mismatch Repair

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