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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Related Experiment Video

Updated: May 10, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

Approach to diagnosing lower extremity ulcers.

Eri Fukaya¹, David J Margolis

¹Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Dermatologic Therapy

|June 8, 2013

Summary

Chronic leg ulcers stem from venous disease or arterial insufficiency. Accurate diagnosis through history, physical exam, and testing is crucial for effective treatment tailored to the ulcer

Area of Science:

Vascular medicine
Dermatology
Wound care

Background:

Chronic leg ulcers are a significant clinical challenge, often impacting patient quality of life.
Etiology is frequently multifactorial, commonly involving venous disease and peripheral arterial disease.
Appropriate diagnosis is paramount for effective therapeutic strategies.

Purpose of the Study:

To elucidate the primary causes of chronic leg ulcers.
To emphasize the importance of accurate etiological diagnosis for treatment planning.

Main Methods:

Clinical assessment including patient history.
Comprehensive physical examination of the affected limb.
Diagnostic testing to determine underlying vascular or systemic conditions.

Related Experiment Videos

Last Updated: May 10, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

Main Results:

Venous disease and arterial insufficiency (peripheral arterial disease) are the most common etiologies.
A combination of both vascular conditions can also lead to chronic leg ulcers.
Diagnostic approach relies on integrating clinical findings with objective testing.

Conclusions:

The etiology of chronic leg ulcers dictates appropriate treatment.
A systematic diagnostic approach is essential for managing these complex wounds.
Understanding the underlying cause ensures targeted and effective patient care.