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Occlusive vascular stapling in a canine inferior vena cava model
Journal of Vascular Surgery
|July 1, 1990
Summary
A novel canine model demonstrated that a triple staggered staple line securely occludes the inferior vena cava (IVC). This method withstands high pressures immediately and after six weeks, showing excellent healing and no adverse reactions.
Area of Science:
- Vascular Surgery
- Biomedical Engineering
- Surgical Innovation
Background:
- Inferior vena cava (IVC) resection requires secure closure methods.
- Evaluating novel stapling techniques for venous anastomosis is crucial.
Purpose of the Study:
- To assess the biomechanical and clinical efficacy of a cartridge stapler with a triple staggered staple line for IVC resection.
- To evaluate the integrity and healing of the staple line in a canine model.
Main Methods:
- A canine model was developed for IVC occlusion and resection.
- Eighteen dogs underwent IVC occlusion, excision, and stapling.
- Staple line integrity, bursting pressure, and histological changes were assessed immediately and at 6 weeks.
Main Results:
- All staple lines were intact immediately post-procedure, with bursting pressures of 150-300 mm Hg.
- At 6 weeks, no staple line leakage was observed despite chronic pressures up to 39 cm H2O.
- Histological examination showed normal reendothelialization and no inflammation or foreign body reaction.
Conclusions:
- The triple staggered staple line provides secure and rapid IVC occlusion.
- This stapling technique withstands supraphysiologic stresses both acutely and chronically.
- The method demonstrates excellent healing characteristics and is suitable for IVC resection.