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Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Partial posterior hyaloidectomy for macular disorders.

J H Kim¹, S W Kang, Y T Kim

¹Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine, Seoul, Korea. swkang@skku.edu

Eye (London, England)

|June 8, 2013

Summary

Partial posterior hyaloidectomy (PPH) significantly reduces iatrogenic retinal breaks during induced posterior vitreous detachment (IPVD) surgery. This technique offers a safer alternative for retinal break prevention in vitreoretinal procedures.

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Area of Science:

Ophthalmology
Retinal Surgery
Vitreoretinal Interface

Background:

Iatrogenic retinal breaks are a complication of inducing posterior vitreous detachment (IPVD).
Conventional 23-gauge total vitrectomy with extensive IPVD carries a risk of peripheral retinal breaks.

Purpose of the Study:

To evaluate the efficacy of partial posterior hyaloidectomy (PPH) in preventing iatrogenic retinal breaks.
To compare the incidence of retinal breaks after PPH versus conventional total vitrectomy during IPVD.

Main Methods:

A prospective, interventional case series of 59 patients undergoing PPH before IPVD for epiretinal membrane or macular hole.
Vitreous gel removal was limited to an area beyond the temporal vascular arcade.
Comparison with 57 eyes undergoing conventional 23-gauge total vitrectomy with extensive IPVD.

Main Results:

The incidence of peripheral retinal breaks was significantly lower after PPH (3.4%) compared to conventional vitrectomy (15.8%, P=0.023).
Follow-up averaged 14.3 months.
No patients reported postoperative floaters.

Conclusions:

Partial posterior hyaloidectomy (PPH) is an effective method for preventing iatrogenic peripheral retinal breaks.
PPH offers a reduced risk of retinal breaks associated with induced posterior vitreous detachment.