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Unilateral movement disorder as a presenting sign of paediatric post-varicella angiopathy

Marcel M M Bulder1, Robert ten Houten, Catharina J M Klijn

  • 1Department of Neurology, UMC Utrecht, Utrecht, The Netherlands. M.M.M.Bulder@umcutrecht.nl

BMJ Case Reports
|June 8, 2013
PubMed

Insights

Diagnosing childhood ischaemic stroke can be challenging. Post-varicella angiopathy (PVA) is a common cause, even without a recent rash, and requires prompt medical history review and imaging for early detection and treatment.

Area of Science:

  • Neurology
  • Pediatrics
  • Vascular Neurology

Background:

  • Childhood ischaemic stroke diagnosis presents significant challenges.
  • Post-varicella angiopathy (PVA) is a recognized and frequent cause of stroke in children.
  • PVA commonly affects the basal ganglia region of the brain.

Observation:

  • Children presenting with unilateral involuntary movements may have cerebral infarction.
  • PVA should be considered in the differential diagnosis of childhood stroke.
  • Normal cerebrospinal fluid and absence of a recent rash do not exclude PVA.

Findings:

  • Medical history is crucial for identifying potential PVA cases.
  • Intracranial vascular imaging aids in the early diagnosis of PVA.
  • Prompt diagnosis facilitates timely and effective treatment strategies.

Implications:

  • Early recognition of PVA can prevent long-term neurological deficits in children.
  • Understanding PVA's presentation improves diagnostic accuracy for pediatric stroke.
  • This highlights the importance of considering PVA in pediatric neurology evaluations.

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