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Updated: May 10, 2026

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
Published on: May 19, 2015
Psychomotor retardation and externally oriented thinking in major depression
Maria Luca1, Antonina Luca, Carmela Calandra
1Department of Medical and Surgery Specialties, Psychiatry Unit of the University Hospital "Policlinico-Vittorio Emanuele" of Catania (Sicily), Italy.
This study found a link between alexithymia and depression symptoms in patients and controls. Psychomotor retardation in depressed patients correlated with externally oriented thinking, suggesting cognitive factors influence depressive presentation.
Area of Science:
- Psychiatry
- Clinical Psychology
- Affective Disorders
Background:
- Alexithymia, characterized by difficulty identifying and describing emotions, is often observed in psychiatric conditions.
- Depression is a prevalent mood disorder with diverse symptom presentations.
- Understanding the relationship between alexithymia and depression is crucial for effective diagnosis and treatment.
Purpose of the Study:
- To explore correlations between alexithymia and depressive states.
- To examine relationships using specific subscales of the Toronto Alexithymia Scale (TAS-20) and the Hamilton Rating Scale for Depression (HAM-D).
Main Methods:
- Assessed 75 patients with Unipolar Depression and 63 controls using the HAM-D and TAS-20.
- Divided participants into age subgroups (30-60 and 61-80 years).
- Investigated correlations between alexithymia and depressive symptoms globally and by subscale.
Main Results:
- Positive correlations found between HAM-D and TAS-20 total scores in patients.
- HAM-D psychomotor retardation correlated with TAS-20 total score and subscales in patients, particularly females and those aged 30-60.
- Anxiety/somatization correlated with TAS-20 in the control group.
Conclusions:
- Confirmed the link between alexithymia and affective symptoms in both patients and controls.
- Highlighted the correlation between psychomotor retardation and externally oriented thinking in patients.
- Suggested cognitive theories may explain how externally oriented thinking contributes to psychomotor retardation in depression.
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