Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Art and science.

Journal of the American College of Cardiology·2014
Same author

Fundamental concepts of effective troponin use: important principles for internists.

The American journal of medicine·2014
Same author

A prospective randomized controlled study of erythromycin on gastric and small intestinal distention: implications for MR enterography.

European journal of radiology·2014
Same author

Delayed transcatheter heart valve migration and failure.

JACC. Cardiovascular imaging·2014
Same author

Aortic valve replacement for severe aortic valve stenosis in the nonagenarian patient.

The Annals of thoracic surgery·2014
Same author

Snake eyes.

Journal of the American College of Cardiology·2014

Related Experiment Video

Updated: May 10, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

An update on transcatheter aortic valve replacement.

Mario Gössl, David R Holmes

    Current Problems in Cardiology
    |June 11, 2013
    PubMed
    Summary

    Transcatheter aortic valve replacement (TAVR) offers a life-saving option for severe aortic stenosis patients previously denied treatment. TAVR significantly reduces mortality and is noninferior to traditional surgery in high-risk individuals.

    Area of Science:

    • Cardiovascular Medicine
    • Interventional Cardiology
    • Medical Technology

    Background:

    • Severe symptomatic aortic stenosis historically left inoperable patients with limited options.
    • Transcatheter aortic valve replacement (TAVR) has emerged as a significant advancement.
    • Over 50,000 TAVRs have been performed globally, primarily in Europe.

    Purpose of the Study:

    • To evaluate the efficacy and safety of TAVR in patients with severe symptomatic aortic stenosis.
    • To compare TAVR outcomes against medical therapy and traditional open-heart surgery.

    Main Methods:

    • Analysis of short-term results from the Placement of Aortic Transcatheter Valve (PARTNER) I trial.
    • Review of long-term European/Canadian registry data for TAVR outcomes.

    Related Experiment Videos

    Last Updated: May 10, 2026

    Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
    06:04

    Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

    Published on: August 8, 2025

    Main Results:

    • TAVR demonstrated a significant reduction in mortality compared to medical therapy alone in inoperable patients (cohort B).
    • TAVR proved noninferior to open aortic valve replacement in high-risk operable patients (cohort A).

    Conclusions:

    • TAVR is a viable and effective treatment for severe symptomatic aortic stenosis, improving survival rates.
    • Ongoing technical advancements and operator experience are expanding TAVR's applicability to lower-risk populations.