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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...

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Related Experiment Video

Updated: May 10, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Everyday memory in children after resective epilepsy surgery.

Colby Oitment1, Ellen Vriezen, Mary Lou Smith

  • 1Department of Psychology, University of Toronto Mississauga, Mississauga, ON, Canada.

Epilepsy & Behavior : E&B
|June 11, 2013
PubMed
Summary

Children with intractable epilepsy show poorer everyday memory compared to healthy peers. Memory function in these children does not significantly change over time or after epilepsy surgery.

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Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
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Assessment of Memory Function in Pilocarpine-induced Epileptic Mice

Published on: June 4, 2020

Area of Science:

  • Pediatric Neurology
  • Neuropsychology
  • Epilepsy Research

Background:

  • Intractable epilepsy in childhood can impact cognitive functions, particularly memory.
  • Understanding the real-world memory challenges faced by these children is crucial for effective support.
  • Previous research has highlighted memory deficits in epilepsy, but longitudinal data on everyday memory is limited.

Purpose of the Study:

  • To investigate parent-reported everyday memory and objectively measured memory performance in children with intractable epilepsy.
  • To examine changes in memory over a 2-year period in children with epilepsy.
  • To assess the impact of resective surgery and seizure outcome on memory in this population.

Main Methods:

  • A cohort of 119 children with intractable epilepsy and 57 healthy controls participated.
  • Parental reports on children's everyday memory were collected.
  • Children with epilepsy underwent standardized objective memory testing at baseline and after 2 years.
  • Surgical status and seizure outcomes were recorded for the epilepsy group.

Main Results:

  • Children with intractable epilepsy demonstrated poorer everyday memory compared to healthy controls at baseline.
  • No significant changes in memory function were observed over the 2-year follow-up period in the epilepsy group.
  • Neither epilepsy surgery nor seizure outcome was associated with significant changes in memory performance or parent-reported everyday memory.

Conclusions:

  • Intractable childhood epilepsy is linked to persistent difficulties in applying memory skills in daily life.
  • Resective epilepsy surgery does not appear to alter parents' perceptions of their child's everyday memory or objective memory test results.
  • Long-term memory support strategies may be necessary for children with intractable epilepsy, irrespective of surgical intervention.