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Related Experiment Video

Updated: May 10, 2026

Iris Fixation via External Pentagram Suturing

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Published on: May 5, 2022

Central anterior chamber depth changes after prophylactic laser iridotomy.

Amir Faramarzi¹, Shahin Yazdani, Mohammad Pakravan

¹Ophthalmic Research Center and Department of Ophthalmology, Labbafinejad Medical Center, Shahid Beheshti Medical University, Tehran, Iran. amirfaramarzy@yahoo.com

Optometry and Vision Science : Official Publication of the American Academy of Optometry

|June 11, 2013

Summary

Laser peripheral iridotomy (LPI) did not significantly alter central anterior chamber depth (CACD) in primary angle closure suspect eyes. This study found no biometric changes after LPI, suggesting it does not impact anterior chamber dimensions.

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Area of Science:

Ophthalmology
Anterior Segment Surgery
Ocular Biometry

Background:

Primary angle closure suspect (PACS) eyes are at risk of developing angle closure glaucoma.
Laser peripheral iridotomy (LPI) is a common treatment to improve aqueous humor flow.
The effect of LPI on ocular biometry in PACS eyes requires further investigation.

Purpose of the Study:

To assess the impact of LPI on central anterior chamber depth (CACD) and other biometric parameters.
To evaluate changes in lens thickness, axial length, and central corneal thickness post-LPI.

Main Methods:

An interventional case series involving eyes classified as primary angle closure suspect.
Biometric measurements using Lenstar biometer before and 6 weeks after LPI.
Key parameters measured: CACD, lens thickness, axial length, central corneal thickness.

Main Results:

Forty eyes from 40 patients were analyzed (mean age 56.5 years).
Mean CACD showed no significant change (2.07 mm pre-LPI vs. 2.08 mm post-LPI, p=0.8).
No significant alterations were observed in lens thickness, axial length, or central corneal thickness post-LPI.

Conclusions:

Laser peripheral iridotomy does not alter central anterior chamber depth in primary angle closure suspect eyes.
Biometric parameters remain stable after LPI in this patient cohort.
Lenstar biometry confirms no significant change in CACD following LPI.