Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

An Annual Review of Important Apheresis Articles in 2025 From the American Society for Apheresis Attending Physician Subcommittee.

Journal of clinical apheresis·2026

Same author

An Annual Review of Important Apheresis Articles in 2024 From the American Society for Apheresis Attending Physician Subcommittee.

Journal of clinical apheresis·2025

Same author

How do I overcome apheresis collection challenges for sickle cell disease gene therapy.

Transfusion·2025

Same author

Quality indicators for cell collections for immune effector cell and gene therapy: recommendations from the American Society for Apheresis.

Cytotherapy·2025

Same author

Red Cell Transfusion in Acute Myocardial Infarction: AABB International Clinical Practice Guidelines.

Annals of internal medicine·2025

Same author

HMA/VEN treatment modifications and associated outcomes in <i>IDH</i>-mutant AML.

Leukemia & lymphoma·2024

Search research articles

Related Experiment Video

Updated: May 10, 2026

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro

Published on: March 21, 2015

Low-level laser therapy for fat layer reduction: a comprehensive review.

Pinar Avci¹, Theodore T Nyame, Gaurav K Gupta

¹Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

Lasers in Surgery and Medicine

|June 11, 2013

Summary

Low-level laser therapy (LLLT) shows promise for fat and cellulite reduction, with potential benefits for blood lipid profiles. Further research is needed to confirm its efficacy as a standalone treatment and fully elucidate its mechanisms.

Keywords:

LLLT body contouring cellulite cholesterol fat lipoplasty liposuction

More Related Videos

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Published on: May 23, 2025

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Related Experiment Videos

Last Updated: May 10, 2026

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro

Published on: March 21, 2015

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation

Published on: May 23, 2025

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Area of Science:

Biomedical Engineering
Dermatology
Aesthetic Medicine

Background:

Low-level laser therapy (LLLT) is a noninvasive treatment for pain, inflammation, and tissue regeneration.
LLLT is increasingly explored for noninvasive body contouring, cellulite reduction, and improving blood lipid profiles.
LLLT may enhance fat graft survival in autologous fat transfer procedures.

Purpose of the Study:

To review the literature on LLLT for fat layer reduction.
To evaluate the efficacy and safety of LLLT in fat reduction.
To understand the proposed mechanisms of action for LLLT in fat reduction.

Main Methods:

A literature review was conducted.
Studies included pre-clinical and clinical research on LLLT for fat layer reduction.
The review focused on mechanism of action, efficacy, and safety.

Main Results:

LLLT demonstrates potential for fat and cellulite reduction and blood lipid profile improvement with minimal side effects.
Proposed mechanisms include creating transient pores in adipocytes for lipid release and activating complement cascade to induce adipocyte apoptosis.
Studies suggest LLLT is safe and effective for fat layer reduction.

Conclusions:

Current studies indicate LLLT is safe and effective for fat layer reduction.
More research is required to establish LLLT's efficacy as a standalone fat reduction procedure.
Further investigation is needed to fully identify the mechanisms of action for LLLT in fat reduction.