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Updated: May 10, 2026

Green Synthesis, Characterization, Encapsulation, and Measurement of the Release Potential of Novel Alkali Lignin Micro-/Submicron Particles
Published on: March 1, 2024
[Study on preparation of total flavones in Glechoma longituba sustained-release tablets and its in vitro release]
Chun-Ling Yuan1, Liang Zhao, Ya-Juan Wang
1Liaoning Medical College, Jinzhou 121001, China. yutong8747@sina.com
Objective:
To study the preparation of total flavones in Glechoma longituba sustained-release tablets and evaluate its releasing features in vitro.
Methods:
Orthogonal experiment (L(9)3(4)) was used to optimize the process of preparation of total flavones in Glechoma longituba sustained-release tablets. Investigated the release effect in vitro of optimization test result.
Results:
The optimized prescription was HPMC-K4M and carbopol 934p account for 30% of the total tablet weight, their dosage ratio was 2: 1; Lactose as additives, 20% dosage; 5% PVP ethanol as adhesives, and compressed the wet granule of the materials into the total flavones in Glechoma longituba sustained-release tablets. The released profiles of the sustained-release tablets followed zero-order equation.
Conclusion:
The sustained-release effect of total flavones in Glechoma longituba sustained-release tablets is good, the preparation craft is easy and feasible and worth widely promoting.
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