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Updated: May 10, 2026

Development of a Microfluidics-Based Approach for Investigating Microtubule Polymer Mechanics
Published on: May 30, 2025
Dynamic guiding of motor-driven microtubules on electrically heated, smart polymer tracks
Viktor Schroeder1, Till Korten, Heiner Linke
1Max Planck Institute of Molecular Cell Biology and Genetics , 01307 Dresden, Germany.
Abstract:
Biomolecular motor systems are attractive for future nanotechnological devices because they can replace nanofluidics by directed transport. However, the lack of methods to externally control motor-driven transport along complex paths limits their range of applications. Based on a thermo-responsive polymer, we developed a novel technique to guide microtubules propelled by kinesin-1 motors on a planar surface. Using electrically heated gold microstructures, the polymers were locally collapsed, creating dynamically switchable tracks that successfully guided microtubule movement.
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