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Assessing the need for a research ethics remediation program.

James M DuBois¹, Emily E Anderson, John Chibnall

¹Bander Center for Medical Business Ethics, Saint Louis University, St. Louis, MO, USA. jamesofthewood@gmail.com

Clinical and Translational Science

|June 12, 2013

Summary

This summary is machine-generated.

Research misconduct is frequent at US institutions, with most investigating violations of procedure, integrity, and policy. Many research integrity officers and institutional review board chairs expressed interest in remediation programs like RePAIR.

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Area of Science:

Medical Research Ethics
Research Administration
Academic Integrity

Background:

The Restoring Professionalism and Integrity in Research (RePAIR) program was developed to address remediation needs for investigators violating research regulations.
Leading research institutions in the United States face challenges in managing research misconduct.

Purpose of the Study:

To determine the frequency and types of research misconduct at US institutions.
To assess institutional responses to misconduct.
To gauge interest in formal remediation programs for investigators.

Main Methods:

An online questionnaire was emailed to research integrity officers (RIOs) and institutional review board (IRB) chairs at 194 US medical and doctoral institutions.
161 individuals (44%) responded, representing 66% of institutions.
Data analyzed included investigation frequency, types of misconduct, and interest in remediation.

Main Results:

96% of institutions with responding RIOs and IRB chairs had investigated at least one case in the past two years.
The most common misconduct involved procedural violations, informed consent, research integrity (fabrication, falsification, plagiarism), privacy, and conflict of interest.
Most RIOs and IRB chairs showed interest in the RePAIR program, despite concerns about cost and faculty resistance.

Conclusions:

Research misconduct is a prevalent issue in US research institutions, necessitating effective remediation strategies.
The RePAIR program shows promise as a solution for addressing investigator misconduct.
Institutional buy-in and addressing practical concerns like cost and faculty resistance are crucial for program success.