Related Experiment Video
Updated: May 10, 2026

04:36
The Examination of Peroxidase-Positive Leukocytes in Semen
Published on: January 19, 2024
Testing for hypersensitivity to seminal fluid-free spermatozoa.
Michael Carroll1, Gregory Horne, Richard Antrobus
1Department of Reproductive Medicine, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK. michael.carroll@mmu.ac.uk
Human Fertility (Cambridge, England)
|June 12, 2013
Summary
Hypersensitivity to human semen (HHS) can cause severe reactions, including anaphylaxis. Allergy skin prick tests using washed sperm, not whole semen, can safely identify specific allergies and reduce risks.
Area of Science:
- Reproductive Immunology
- Allergy and Immunology
- Urology
Background:
- Hypersensitivity to human semen (HHS) is an increasingly recognized condition.
- Symptoms range from local reactions to systemic anaphylaxis.
- Accurate diagnosis is crucial for effective management and risk mitigation.
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