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Updated: May 10, 2026

Green Synthesis of Quinoline-Based Ionic Liquid
Published on: September 27, 2024
Poly(4-vinylpyridine) supported acidic ionic liquid: a novel solid catalyst for the efficient synthesis of
Junke Wang1, Yingxiao Zong, Rugang Fu
1Key Laboratory of Hexi Corridor Resources Utilization of Gansu Universities, College of Chemistry and Chemical Engineering, Hexi University, Zhangye 734000, China; School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Abstract:
A novel poly(4-vinylpyridine) supported acidic ionic liquid catalyst was synthesized by the reaction of 4-vinylpyridine with 1,3-propanesultone, followed by the polymerization and the addition of the heteropolyacid. Due to the combination of polymer features and ionic liquid, it acted as a heterogeneous catalyst to effectively catalyze the cyclocondensation reaction of anthranilamide with aldehydes under ultrasonic irradiation and afforded the corresponding 2,3-dihydro-4(1H)-quinazolinones compounds in good to excellent yields. In addition, the catalyst could be easily recovered by the filtration and reused six times without significant loss of catalytic activity. More importantly, the use of ultrasonic irradiation can obviously accelerate the reaction.
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