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Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics

Nicholas T Ventham1, Nicholas A Kennedy, Elaine R Nimmo

  • 1Gastrointestinal Unit, Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland. nventham@staffmail.ed.ac.uk

Gastroenterology
|June 12, 2013
PubMed

Keywords:
CDCpGCrohn’s DiseaseCrohn’s diseaseDNA MethylationDNA methyltransferaseDNMTEWASEpigeneticsGWASHATHDACHDACiIBDILNF-κBPBMCSNPT-helperTNFThUCUlcerative Colitiscytosine-guanine dinucleotidesepigenome-wide methylation association studiesgenome-wide association studieshistone acetyl transferasehistone deacetylasehistone deacetylatase inhibitorsinflammatory bowel diseaseinterleukinmRNAmessenger RNAmiRmicroRNAnuclear factor κBperipheral blood mononuclear cellsingle nucleotide polymorphismtumor necrosis factorulcerative colitis

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