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Updated: May 10, 2026

Techniques of Endoscopic Ossiculoplasty
Published on: January 26, 2024
Over the scope clip: technique and expanding clinical applications
Shashideep Singhal1, Kinesh Changela, Haris Papafragkakis
1Department of Internal Medicine, Division of Gastroenterology, The Brooklyn Hospital Center, New York Presbyterian Healthcare System, Weill Cornell Medical College, Brooklyn, NY.
The Over-the-Scope Clip (OTSC) system effectively treats gastrointestinal complications, showing high success rates for perforations, leaks, and bleeding. This endoscopic device simplifies procedures and reduces the need for surgery.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Medical Devices
Background:
- Endoscopic and surgical procedures are increasing in frequency and complexity.
- This rise leads to a greater incidence of associated complications.
Purpose of the Study:
- To review the clinical applications and efficacy of the Over-the-Scope Clip (OTSC) system.
- To evaluate the OTSC system's role in managing gastrointestinal complications.
Main Methods:
- A comprehensive literature search was performed for human studies on OTSC applications from 2001 to 2012.
- Key terms used were "endoscopy" and "over the scope clip".
- Data on indications, efficacy, complications, and limitations were systematically recorded.
Main Results:
- OTSC demonstrated high success rates: 75-100% for perforations, 38-100% for fistulas, 50-100% for anastomotic leaks, and 71-100% for bleeding lesions.
- A 100% success rate was noted for managing postbariatric surgery weight gain via gastrojejunal pouch dilation.
- The OTSC system is characterized by ease of use and favorable outcomes.
Conclusions:
- The Over-the-Scope Clip (OTSC) system offers a user-friendly approach to managing gastrointestinal complications.
- Its application can significantly decrease morbidity and mortality associated with endoscopic procedures.
- OTSC facilitates avoiding surgical intervention in numerous clinical scenarios.
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