Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 10, 2026

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System
06:58

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System

Published on: June 13, 2010

Single cell detection using a magnetic zigzag nanowire biosensor.

Hao-Ting Huang1, Tzong-Rong Ger, Ya-Hui Lin

  • 1Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu 300, Taiwan.

Lab on a Chip
|June 12, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantitative measurement of agonistic behaviors of intra- and interspecifics of Gryllus bimaculatus and Acheta domesticus by using DeepLabCut.

Scientific reports·2026
Same author

Robust Non-Invasive Cardiac Index Prediction via Feature Integration and Data-Augmented Neural Networks.

Bioengineering (Basel, Switzerland)·2026
Same author

Mitochondrial ATP production promotes T cell differentiation and function by regulating chromatin accessibility.

bioRxiv : the preprint server for biology·2026
Same author

Digitally programmable microfluidic valving for autonomous, high-resolution continuous chromatographic purification.

Lab on a chip·2026
Same author

A post-translational regulatory map of chronic antigen-driven human T cell dysfunction.

bioRxiv : the preprint server for biology·2026
Same author

Antisense Dipeptide Repeat Proteins Drive Widescale Purine Metabolism Aberration in <i>C9orf72</i> Amyotrophic Lateral Sclerosis via ADA.

International journal of molecular sciences·2026
Same journal

Tunable self-assembling cellular microarray for single-neutrophil vital and suicidal extracellular traps.

Lab on a chip·2026
Same journal

Precise programmable tumor cell subpopulation sorting <i>via</i> an electromagnetic microfluidic platform.

Lab on a chip·2026
Same journal

Bridging dimensions: combining one- and two-photon 3D printing for microfluidic device fabrication.

Lab on a chip·2026
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
See all related articles

This study presents a magnetic zigzag nanowire device for single cell biosensing. The device enables multi-directional detection and uses stray fields to attract and fix magnetic cells for enhanced sensing.

Area of Science:

  • Nanotechnology
  • Biosensing
  • Magnetics

Background:

  • Single cell biosensing requires sensitive and specific detection methods.
  • Magnetic nanoparticles offer unique properties for biosensing applications.
  • Developing novel sensor platforms is crucial for advancing cellular analysis.

Purpose of the Study:

  • To design and fabricate a magnetic zigzag nanowire device for single cell biosensing.
  • To investigate the magnetoresistance response of the nanowire device to magnetic cells.
  • To evaluate the multi-directional detection capabilities and cell-fixing properties of the sensor.

Main Methods:

  • Fabrication of magnetic zigzag nanowires using electron beam lithography, evaporation, and lift-off.
  • Magnetoresistance measurements before and after magnetic cell attachment.

More Related Videos

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
12:20

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications
11:25

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications

Published on: April 21, 2016

Related Experiment Videos

Last Updated: May 10, 2026

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System
06:58

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System

Published on: June 13, 2010

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
12:20

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications
11:25

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications

Published on: April 21, 2016

  • Analysis of sensor performance under varying magnetic field directions and nanowire widths.

    • Main Results:

    • The magnetic zigzag nanowire device demonstrated multi-directional detection capabilities.
    • Highest switching field variation was observed in 150 nm nanowires with perpendicular magnetic fields.
    • Highest magnetoresistance ratio variation was observed in 800 nm nanowires with perpendicular magnetic fields.
    • Trench-structured substrate effectively immobilizes magnetic cells in fluidic environments.
    • Stray fields from nanowire corners actively attract magnetic cells for detection.

    Conclusions:

    • The magnetic zigzag nanowire device is a promising platform for single cell biosensing.
    • Nanowire width and magnetic field orientation significantly influence sensor performance.
    • The integrated trench and stray field attraction mechanism enhances cell capture and detection efficiency.