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Published on: January 29, 2018
Advanced bone age in children with Blount disease: a case-control study.
Sanjeev Sabharwal1, Sara M Sakamoto, Caixia Zhao
1Department of Orthopedics, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA. sabharsa@umdnj.edu
Journal of Pediatric Orthopedics
|June 12, 2013
Summary
Children with Blount disease exhibit advanced skeletal maturity compared to their peers. This advanced bone age can influence surgical planning for limb deformities, necessitating preoperative assessment.
Area of Science:
- Pediatric Orthopedics
- Skeletal Development
- Growth Plate Dynamics
Background:
- Blount disease often presents with obesity and multiplanar limb deformities in children.
- Current surgical treatments like guided growth and osteotomy have variable outcomes.
- The skeletal maturity of children with Blount disease has not been previously investigated.
Purpose of the Study:
- To investigate whether children with Blount disease have advanced skeletal maturity compared to age-matched controls.
- To evaluate the relationship between skeletal age and chronologic age in Blount disease.
- To assess the influence of disease onset and chronologic age on skeletal maturity discrepancies.
Main Methods:
- Comparative study of 33 patients with Blount disease and 33 age- and sex-matched controls.
- Analysis of skeletal age (bone age) versus chronologic age.
- Evaluation of factors influencing the discrepancy between skeletal and chronologic age.
Main Results:
- Patients with Blount disease had a significantly higher mean BMI (39 kg/m2) than controls (23 kg/m2).
- Bone age was advanced by 16 months in the Blount disease group versus 5 months in controls.
- Early-onset Blount disease showed a greater bone age advancement (26 months) than late-onset (10 months).
Conclusions:
- Children with Blount disease demonstrate advanced skeletal maturity.
- The gap between bone age and chronologic age narrows with increasing age.
- Preoperative bone age assessment is recommended for surgical planning in Blount disease to optimize correction of lower limb deformities.
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