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Identifying the metastatic seeds of breast cancer

Angera H Kuo1, Michael F Clarke

  • 1Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California, USA.

Nature Biotechnology
|June 12, 2013
PubMed
Abstract

No abstract available in PubMed .

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Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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