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Hereditary cerebellar degeneration with downbeat nystagmus. A case and it's treatment
H W McConnell1, C L Darlington, P F Smith
1Department of Physiology, University of Otago, Dunedin, New Zealand.
Acta Neurologica Scandinavica
|May 1, 1990
Abstract:
We present a female patient of 48 years with downbeat nystagmus (DBN), moderate impairment of coordination testing and a family history of cerebellar ataxia. We report that a single 2 mg dose of clonazepam (following Currie & Matsuo) resulted in a virtual disappearance of nystagmus and of the patient's symptom of oscillopsia. This result is interpreted in terms of current models of DBN.