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Related Concept Videos

Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Antiasthma Drugs: Methylxanthines01:24

Antiasthma Drugs: Methylxanthines

Theophylline, a member of the methylxanthine class of bronchodilators, has long been used in asthma management. While its exact mechanism of action is not fully understood, it is believed to have multiple effects on various cellular processes.
Theophylline is thought to inhibit phosphodiesterase enzymes, increasing intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). This rise in cAMP and cGMP concentrations stimulates cardiac function,...

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Related Experiment Video

Updated: May 10, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
09:50

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade

Published on: August 14, 2019

Flavonoids and asthma.

Toshio Tanaka1, Ryo Takahashi

  • 1Department of Clinical Application of Biologics, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan. ttanak@imed3.med.osaka-u.ac.jp

Nutrients
|June 12, 2013
PubMed
Summary
This summary is machine-generated.

Flavonoids, plant compounds found in fruits and vegetables, show promise in managing asthma symptoms. Further research is needed to confirm their role as a dietary treatment or preventive strategy for this chronic respiratory condition.

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A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
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Last Updated: May 10, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
09:50

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade

Published on: August 14, 2019

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

Area of Science:

  • Nutrition Science
  • Immunology
  • Respiratory Medicine

Background:

  • Asthma is a chronic respiratory disease with increasing global prevalence, potentially linked to environmental factors like diet.
  • Flavonoids, plant polyphenols in fruits and vegetables, exhibit antioxidant, anti-allergic, and immune-modulating properties.
  • These properties suggest flavonoids may counteract key asthma mechanisms, including inflammation and immune responses.

Purpose of the Study:

  • To review the scientific literature on the effects of flavonoids on asthma.
  • To evaluate the potential of flavonoids as a dietary intervention for asthma management and prevention.

Main Methods:

  • Literature review of studies on flavonoids and asthma.
  • Analysis of research including animal models, epidemiological studies, and clinical trials.

Main Results:

  • Flavonoids demonstrate beneficial effects in animal models of asthma.
  • Epidemiological studies suggest a positive correlation between flavonoid intake and asthma.
  • Limited clinical trials indicate ameliorative effects of flavonoids on asthma symptoms.

Conclusions:

  • Flavonoids possess properties beneficial for asthma, including antioxidant and anti-allergic activities.
  • Evidence from animal and human studies suggests a potential role for flavonoids in asthma management.
  • Further clinical validation is required to establish flavonoids as a dietary treatment or preventive strategy for asthma.