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Hypertonic saline in elevated intracranial pressure: past, present, and future
Salim Surani1, Geoff Lockwood2, Melissa Y Macias2
1Division of Pulmonary and Critical Care Medicine, Texas A&M University, TX, USA srsurani@hotmail.com.
Abstract:
Hypertonic Saline (HS) has been a proven and effective therapy and a safe alternative to mannitol in patients with increase intracranial pressure (ICP). We hereby present a case of 25-year-old women with intracranial bleed secondary to right parietal arteriovenous malformation. Patient underwent surgery for evacuation of hematoma and resection of arteriovenous malformation. Post- operative course was complicated by recurrent episodes of elevated ICP. She received total of 17 doses of 23.4% HS and 30 doses of mannitol with good outcome. Despite reluctance from some clinicians to use HS, hypertonic saline seems to be a safe and effective therapy.
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