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Updated: May 10, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Reduced cognitive function predicts functional decline in patients with heart failure over 12 months
Michael L Alosco1, Mary Beth Spitznagel2, Ronald Cohen3
1Department of Psychology, Kent State University, USA Malosco@kent.edu.
Heart failure patients experience significant declines in daily activities over 12 months. Cognitive impairment at baseline predicts this functional decline, highlighting the need for cognitive screening in heart failure management.
Area of Science:
- Gerontology
- Cardiology
- Neuroscience
Background:
- Heart failure (HF) patients commonly experience impaired activities of daily living (ADL), contributing to higher mortality and hospitalization rates.
- Cognitive impairment is prevalent in HF, but its predictive value for long-term functional decline remains unclear.
Purpose of the Study:
- To investigate the longitudinal pattern of ADL in individuals with HF.
- To determine if baseline cognitive status predicts future functional decline in HF patients.
Main Methods:
- 110 HF patients completed the Lawton-Brody Instrumental Activities of Daily Living (IADL) scale and the Modified Mini-Mental Status Examination (3MS) at baseline and 12-month follow-up.
- Three composite ADL scores (total, instrumental, basic) were derived from the Lawton-Brody scale.
Main Results:
- HF patients reported significant baseline impairments in instrumental ADL, such as shopping and food preparation.
- A significant decline in total and instrumental ADL was observed from baseline to 12 months (p<0.05).
- Poorer baseline 3MS scores predicted worse total ADL performance at 12 months, including increased dependence in shopping, driving, and ambulation (p<0.05).
Conclusions:
- HF patients exhibit significant functional decline over a 12-month period.
- Brief cognitive assessments can identify HF patients at higher risk for functional decline.
- Cognitive screening may help identify HF patients needing assistance with ADL tasks.
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