Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomarker analyses from the phase III randomized CLEAR trial: lenvatinib plus pembrolizumab versus sunitinib in advanced renal cell carcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

Evaluating the genetic consequences of population subdivision as it unfolds and how to best mitigate them: A rare story about koalas.

Molecular ecology·2023
Same author

Associations of tissue tumor mutational burden and mutational status with clinical outcomes in KEYNOTE-042: pembrolizumab versus chemotherapy for advanced PD-L1-positive NSCLC.

Annals of oncology : official journal of the European Society for Medical Oncology·2023
Same author

How microbiomes can help inform conservation: landscape characterisation of gut microbiota helps shed light on additional population structure in a specialist folivore.

Animal microbiome·2022
Same author

Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab.

Annals of oncology : official journal of the European Society for Medical Oncology·2021
Same author

Molecular determinants of clinical outcomes with pembrolizumab versus paclitaxel in a randomized, open-label, phase III trial in patients with gastroesophageal adenocarcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2021
Same journal

[Macular serpiginous choroiditis complicated by macular hole].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Therapeutic approach in persistent diabetic macular edema].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Preliminary results of treatment with aflibercept].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

MANAGEMENT OF DIABETIC RETINOPATHY, PREVALENCE AND CLINICAL CLASSIFICATION.

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Changes in intraocular pressure depending on posture].

Oftalmologia (Bucharest, Romania : 1990)·2015
Same journal

[Treatment for penetrating wound caused by metallic intraocular foreign body].

Oftalmologia (Bucharest, Romania : 1990)·2015
See all related articles

Related Experiment Video

Updated: May 10, 2026

System for Focal, Closed-System Central Nervous System Injury
04:02

System for Focal, Closed-System Central Nervous System Injury

Published on: November 29, 2024

[Contusive ocular trauma--case report].

O Muşat1, Corina Coman, R Cristescu

  • 1Spitalul Universitar de Urgenţa Militar Central Bucureşti.

Oftalmologia (Bucharest, Romania : 1990)
|June 13, 2013
PubMed
Summary
This summary is machine-generated.

A 48-year-old man experienced 20 years of decreased vision due to ocular trauma. Surgical intervention, including cataract extraction and retinal detachment repair, led to a favorable visual outcome.

More Related Videos

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
07:27

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

Related Experiment Videos

Last Updated: May 10, 2026

System for Focal, Closed-System Central Nervous System Injury
04:02

System for Focal, Closed-System Central Nervous System Injury

Published on: November 29, 2024

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
07:27

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

Area of Science:

  • Ophthalmology
  • Trauma Surgery

Background:

  • Ocular trauma can lead to long-term visual impairment.
  • Delayed complications include cataract and retinal detachment.

Observation:

  • A 48-year-old male presented with a 20-year history of decreased left eye visual acuity following facial trauma.
  • Examination revealed iridodialysis, corectopia, traumatic cataract, proliferative vitreoretinopathy (PVR), and tractional retinal detachment.

Findings:

  • Surgical management included cataract extraction, posterior vitrectomy with laser photocoagulation, and silicone oil injection.
  • The patient's condition improved post-operatively, with silicone oil removal six months later.

Implications:

  • Prompt and comprehensive surgical intervention is crucial for managing complex post-traumatic ocular conditions.
  • Successful surgical outcomes can be achieved even in cases with long-standing visual compromise due to trauma.