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Habitual snoring in children with previous allergic sensitization
A M Zicari1, F Occasi, A Cesoni Marcelli
1Policlinico Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
Summary
Early allergic sensitization in children under three years old significantly increases the risk of developing habitual snoring (HS) later in life. This risk is amplified when food allergies are combined with inhalant allergies, suggesting a link to upper airway inflammation.
Area of Science:
- Pediatric Allergy
- Sleep Medicine
- Immunology
Background:
- High prevalence of allergy in children with habitual snoring (HS) noted.
- Relationship between early-life allergy and subsequent Sleep Disordered Breathing (SDB) development requires elucidation.
Purpose of the Study:
- To determine the role of early allergic sensitization (under 36 months) to food, with or without airborne allergens, in the development of HS 8-10 years later.
Main Methods:
- 148 children (10-14 years) with a history of food allergy were selected.
- Atopic status assessed via skin prick tests for food and airborne allergens before age 36 months.
- Parental questionnaires collected data on snoring; HS defined as snoring ≥3 times/week.
Main Results:
- Of 54 children sensitized to food allergens alone by age 3, 8 developed HS.
- Of 94 children sensitized to both food and airborne allergens by age 3, 29 developed HS.
- The difference in HS development between these groups was statistically significant (p=0.04).
Conclusions:
- Early allergic sensitization poses a significant risk for developing habitual snoring.
- The risk of HS is higher in children with combined food and inhalant allergies.
- Early upper airway inflammation from allergic triggers may contribute to later SDB development.
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