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Updated: May 10, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
A life-threatening manifestation of tachycardia-induced cardiomyopathy
Riccardo Gerloni1, Elena Abate, Bruno Pinamonti
1aDepartment of Internal Medicine bDepartment of Cardiology cDepartment of Cardiac Surgery dDepartment of Anatomical Pathology, Cattinara Hospital, University of Trieste, Italy.
Abstract:
A 74-year-old man was referred to hospital for sustained dyspnea. The patient was normotensive (110/70 mmHg) with clinical evidence of congestive heart failure. ECG showed atrial flutter (145 bpm). Transthoracic echocardiography demonstrated a mildly dilated left ventricle with severe systolic dysfunction and a big irregular mobile mass, a mildly dilated right ventricle with moderate systolic dysfunction and a large mass protruding into the cavity. The patient was treated surgically for high embolic and sudden death risk after coronarography, which showed a single stenosis (70%) of the left anterior descending coronary. Myocardial biopsy demonstrated interstitial and endocardial fibrosis, no inflammatory pattern. After 6 months of follow-up echocardiography was normal.
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