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Related Concept Videos

Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
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Antiasthma Drugs: β2-Adrenoceptor Agonists

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Antiasthma Drugs: Methylxanthines

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Related Experiment Video

Updated: May 10, 2026

Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
08:33

Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders

Published on: December 4, 2014

Eosinophilia associated with bupropion.

Montserrat García1, Borja Ruiz, Carmelo Aguirre

  • 1Basque Country Pharmacovigilance Unit, Hospital Galdakao-Usansolo, Barrio Labeaga s/n, 48960, Galdakao, Bizkaia, Spain.

International Journal of Clinical Pharmacy
|June 13, 2013
PubMed
Summary

Bupropion, an antidepressant, can cause elevated eosinophil counts, a rare side effect. Discontinuing bupropion led to a decrease in eosinophilia, suggesting a causal link.

Related Experiment Videos

Last Updated: May 10, 2026

Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
08:33

Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders

Published on: December 4, 2014

Area of Science:

  • Pharmacology
  • Clinical Medicine

Background:

  • Bupropion is a widely prescribed antidepressant.
  • Adverse drug reactions require careful monitoring and diagnosis.

Observation:

  • A patient developed myalgia and cough after initiating bupropion.
  • Laboratory tests revealed significant eosinophilia (4.7 × 10^9/L), with previous normal levels.

Findings:

  • Bupropion was identified as the likely cause of drug-induced eosinophilia.
  • Discontinuation of bupropion resulted in a notable reduction in eosinophil count.

Implications:

  • This case highlights bupropion-induced eosinophilia as a potential, albeit rare, adverse effect.
  • Awareness of this association can prevent misdiagnosis and unnecessary investigations.