Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
What is Genetic Engineering?00:49

What is Genetic Engineering?

Overview
Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
Transgenic Organisms00:53

Transgenic Organisms

Overview
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Parameter estimation and assessment of bias in genetic evaluation of carcass traits in Hanwoo cattle using real and simulated data.

Journal of animal science and technology·2024
Same author

Comparison between multiple-trait and random regression models for genetic evaluation of weight traits in Australian meat sheep.

Journal of animal science·2024
Same author

Micro-genetic environmental sensitivity across macro-environments of chickens reared in Burkina Faso and France.

Genetics, selection, evolution : GSE·2023
Same author

Increased Yearling Weight Gain Is Associated with a Distinct Faecal Microbial Profile.

Animals : an open access journal from MDPI·2023
Same author

Including genomic information in the genetic evaluation of production and reproduction traits in South African Merino sheep.

Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie·2023
Same author

The genomic structure of isolation across breed, country and strain for important South African and Australian sheep populations.

BMC genomics·2022

Related Experiment Video

Updated: May 10, 2026

Breeding by Design for Functional Rice with Genome Editing Technologies
09:43

Breeding by Design for Functional Rice with Genome Editing Technologies

Published on: January 3, 2025

Genomic selection in animal breeding programs.

Julius van der Werf1

  • 1School of Environmental and Rural Science, University of New England, Armidale, NSW, Australia.

Methods in Molecular Biology (Clifton, N.J.)
|June 13, 2013
PubMed
Summary
This summary is machine-generated.

Genomic selection significantly boosts animal breeding by providing earlier, more accurate breeding value estimates. This accelerates genetic improvement by 20-100% and enhances selection for difficult traits.

More Related Videos

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
09:35

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research

Published on: August 16, 2017

Improved Genome Editing via Oviductal Nucleic Acids Delivery-based In Vivo Electroporation Technique for Knockout Mice Generation
09:56

Improved Genome Editing via Oviductal Nucleic Acids Delivery-based In Vivo Electroporation Technique for Knockout Mice Generation

Published on: August 26, 2025

Related Experiment Videos

Last Updated: May 10, 2026

Breeding by Design for Functional Rice with Genome Editing Technologies
09:43

Breeding by Design for Functional Rice with Genome Editing Technologies

Published on: January 3, 2025

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
09:35

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research

Published on: August 16, 2017

Improved Genome Editing via Oviductal Nucleic Acids Delivery-based In Vivo Electroporation Technique for Knockout Mice Generation
09:56

Improved Genome Editing via Oviductal Nucleic Acids Delivery-based In Vivo Electroporation Technique for Knockout Mice Generation

Published on: August 26, 2025

Area of Science:

  • Animal genetics
  • Quantitative genetics
  • Livestock breeding

Background:

  • Genomic selection (GS) offers a powerful tool for animal breeding programs.
  • Traditional selection methods face limitations, especially for hard-to-measure or low-heritability traits.
  • Accurate breeding values are crucial for efficient genetic gain in livestock.

Purpose of the Study:

  • To evaluate the impact of genomic selection on animal breeding programs.
  • To highlight the benefits of genomic selection for trait improvement and selection accuracy.
  • To discuss the requirements for effective genomic selection reference populations.

Main Methods:

  • Genomic selection utilizes high-density single nucleotide polymorphism (SNP) markers.
  • Breeding values are estimated using statistical models that incorporate genomic information.
  • Large reference populations with phenotype and genotype data are essential.

Main Results:

  • Genomic selection increases selection accuracy and allows for earlier breeding value estimation.
  • Rates of genetic improvement can increase by 20-100% in species like sheep and dairy cattle.
  • Hard-to-measure traits can be improved more effectively through genomic selection.

Conclusions:

  • Genomic selection is a transformative technology for modern animal breeding.
  • Larger reference populations and smaller effective population sizes enhance genomic prediction accuracy.
  • Strategic use of genomic selection can accelerate genetic progress and improve livestock productivity.