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Related Experiment Video

Updated: May 10, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Published on: December 1, 2023

Multiple myeloma presenting as dysphagia.

Ameen Z Alherabi¹, Ali M Khan, Osama A Marglani

¹Department of Otolaryngology-Head & Neck Surgery, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia. herabi@hotmail.com

Saudi Medical Journal

|June 13, 2013

Summary

This summary is machine-generated.

This case report highlights a rare instance of laryngeal multiple myeloma presenting as dysphagia. Early diagnosis by otolaryngologists is crucial for prompt management of this uncommon plasma cell neoplasm.

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Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

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Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

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Published on: March 1, 2015

Area of Science:

Oncology
Hematology
Otolaryngology

Background:

Plasmacytoma is a neoplastic proliferation of monoclonal plasma cells.
Extramedullary plasmacytoma, including laryngeal involvement, is exceptionally rare.
Multiple myeloma is a malignant plasma cell disorder typically affecting bone marrow.

Observation:

A 77-year-old male presented with dysphagia, a symptom later attributed to multiple myeloma.
The patient was diagnosed with multiple myeloma, a rare cause of laryngeal mass.
The clinical presentation underscores the diagnostic challenges associated with rare head and neck malignancies.

Findings:

The case demonstrates an unusual presentation of multiple myeloma involving the larynx.
Diagnostic difficulties are emphasized due to the rarity of extramedullary plasmacytoma in this location.
The report details the specific clinical course and diagnostic considerations for this rare entity.

Implications:

Increased awareness among otolaryngologists is vital for timely diagnosis of laryngeal plasma cell neoplasms.
Prompt recognition can lead to earlier intervention and improved patient outcomes.
This case contributes to the understanding of rare head and neck cancers and informs clinical practice.