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Updated: May 10, 2026

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
Published on: September 11, 2016
[Progress in research of new human enterovirus types]
Peng Chen1, Ze-Xin Tao, Hai-Yan Wang
1School of Public Health, Shandong University, Jinan 250012, China. chenpeng2403@163.com
New human enteroviruses (HEVs) are emerging globally. This review covers recent advances in understanding HEV molecular typing, evolution, epidemiology, and pathogenesis, particularly concerning enterovirus 71 (EV71) and hand, foot, and mouth disease (HFMD).
Area of Science:
- Virology
- Molecular Biology
- Epidemiology
Context:
- The identification of novel human enteroviruses (HEVs) is increasing due to advanced molecular serotyping techniques.
- Enterovirus 71 (EV71) outbreaks, particularly hand, foot, and mouth disease (HFMD) epidemics in China, highlight the public health threat posed by these viruses.
Purpose:
- To review recent research progress on new enterovirus types.
- To consolidate findings on molecular typing, evolution, epidemiology, and pathogenesis of emerging HEVs.
Summary:
- Molecular serotyping has led to the discovery of numerous new HEV types.
- Recent years have seen significant research into the evolution, epidemiology, and pathogenesis of these novel HEVs.
- Enterovirus 71 remains a key focus due to its association with widespread HFMD outbreaks.
Impact:
- Enhanced understanding of HEV diversity and transmission dynamics.
- Provides a foundation for developing effective public health strategies against HEV infections.
- Highlights the ongoing threat of emerging enteroviruses to global health.
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