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Related Experiment Video

Updated: May 10, 2026

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
14:52

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Published on: January 13, 2018

Xenon consumption during general surgery: a retrospective observational study.

Christian Stoppe1, Achim Rimek1, Rolf Rossaint1,2

  • 1Department of Anaesthesiology, University Hospital, RWTH Aachen, Aachen, Germany.

Medical Gas Research
|June 14, 2013
PubMed
Summary

The ECO mode in the Felix Dual respirator significantly reduces xenon consumption during general surgery anesthesia. This finding addresses the high cost barrier to wider clinical xenon use.

Related Experiment Videos

Last Updated: May 10, 2026

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
14:52

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Published on: January 13, 2018

Area of Science:

  • Anesthesiology
  • Medical Engineering

Background:

  • High costs of xenon limit its clinical application.
  • Evaluating xenon consumption in different delivery modes is crucial for cost-effectiveness.

Purpose of the Study:

  • To assess and compare xenon consumption across various delivery modes (ECO, AUTO, MANUAL) during general surgery anesthesia.
  • To identify the most economical xenon delivery method.

Main Methods:

  • Retrospective analysis of 48 patients undergoing general surgery with balanced xenon anesthesia.
  • Xenon consumption was measured based on the delivery mode during the maintenance phase.

Main Results:

  • Xenon consumption was highest during the initial wash-in phase.
  • ECO mode demonstrated significantly reduced xenon consumption (18.5±3.7L) compared to AUTO (24.7±11.5L) and MANUAL (29.6±14.3L) modes (p=0.033).
  • No significant differences in anesthetic depth, oxygenation, or anesthesia performance were observed across modes.

Conclusions:

  • The closed-circuit respirator Felix Dual effectively reduces xenon consumption when utilizing the ECO mode.
  • The ECO mode presents a cost-effective strategy for xenon anesthesia in general surgery.