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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
14:10

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

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[Intestinal perforation caused by Salmonella typhimurium]

Timme M A J van Vuuren1, Johannes A Wegdam, Marjolijn C A Wegdam-Blans

  • 1Elkerliek ziekenhuis, afd. Heelkunde, Helmond, the Netherlands. tvanvuuren@elkerliek.nl

Nederlands Tijdschrift Voor Geneeskunde
|June 14, 2013
PubMed
Abstract

Insights

Severe complications from non-typhoid Salmonella typhimurium are rare but increasing. This case highlights the potential for serious outcomes even in healthy individuals, emphasizing the need for vigilance.

Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Clinical Microbiology

Background:

  • Non-typhoid Salmonella infections typically cause self-limiting gastroenteritis.
  • Severe complications like bacteremia are usually linked to typhoid Salmonella subspecies (S. typhi, S. paratyphi).
  • This article details a rare case of severe complications from non-typhoid Salmonella.

Observation:

  • A 63-year-old man presented with gastroenteritis-like symptoms.
  • Blood and stool cultures identified Salmonella typhimurium infection.
  • The patient developed intra-abdominal abscesses, abdominal sepsis, and intestinal perforation.

Findings:

  • Salmonella typhimurium caused severe intra-abdominal complications in a healthy individual.
  • The patient required multiple surgical interventions.
  • Recovery was achieved, with the patient symptom-free for six months.

Implications:

  • Severe complications from non-typhoid Salmonella typhimurium are uncommon but possible.
  • Rising incidence of salmonellosis may increase the risk of severe outcomes.
  • Clinicians should consider severe complications in non-typhoid salmonellosis cases.

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