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Updated: May 10, 2026
14:10
Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
Published on: July 29, 2022
[Intestinal perforation caused by Salmonella typhimurium]
Timme M A J van Vuuren1, Johannes A Wegdam, Marjolijn C A Wegdam-Blans
1Elkerliek ziekenhuis, afd. Heelkunde, Helmond, the Netherlands. tvanvuuren@elkerliek.nl
Nederlands Tijdschrift Voor Geneeskunde
|June 14, 2013
Summary
Severe complications from non-typhoid Salmonella typhimurium are rare but increasing. This case highlights the potential for serious outcomes even in healthy individuals, emphasizing the need for vigilance.
Area of Science:
- Infectious Diseases
- Gastroenterology
- Clinical Microbiology
Background:
- Non-typhoid Salmonella infections typically cause self-limiting gastroenteritis.
- Severe complications like bacteremia are usually linked to typhoid Salmonella subspecies (S. typhi, S. paratyphi).
- This article details a rare case of severe complications from non-typhoid Salmonella.
Observation:
- A 63-year-old man presented with gastroenteritis-like symptoms.
- Blood and stool cultures identified Salmonella typhimurium infection.
- The patient developed intra-abdominal abscesses, abdominal sepsis, and intestinal perforation.
Findings:
- Salmonella typhimurium caused severe intra-abdominal complications in a healthy individual.
- The patient required multiple surgical interventions.
- Recovery was achieved, with the patient symptom-free for six months.
Implications:
- Severe complications from non-typhoid Salmonella typhimurium are uncommon but possible.
- Rising incidence of salmonellosis may increase the risk of severe outcomes.
- Clinicians should consider severe complications in non-typhoid salmonellosis cases.
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The location of esophageal perforation can vary, occurring anywhere along the esophagus.
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